School personnel information

写真b

TAKASHIMA Seiji


Keyword

Cardiovascular Medicine, Biochemistry, Pathophysiology

Mail Address

Mail Address

URL

http://www.medbio.med.osaka-u.ac.jp/

Gender

Male

Organization 【 display / non-display

  • 2004.01.01 - 2004.03.31, School of Health and Sport Sciences, Research Assistant

  • 2004.04.01 - 2007.03.31, Health Care Center, Research Assistant

  • 2007.04.01 - 2008.03.31, Health Care Center, Assistant Professor

  • 2008.04.01 - 2013.06.30, Graduate School of Medicine, Associate Professor

  • 2013.07.01 - , Department of Frontier Biosciences, Graduate School of Frontier Biosciences, Professor

  • 2013.07.01 - , Graduate School of Medicine

Education 【 display / non-display

Osaka University Faculty of Medicine  Graduated 1988.03
Osaka University Graduate School, Division of Medicine  Completed 1993.03

Employment Record 【 display / non-display

Osaka University, Health Care Center 2004.04 - 2007.03
Osaka University, Health Care Center 2007.04 - 2008.03
Osaka University Graduate School of Medicine, Department of Medicine, Associate Professor 2008.04 - 2013.06
Osaka University Graduate School of Medicine 2013.07 -

Research topics 【 display / non-display

  • Cardiology-related

 

Academic Papers 【 display / non-display

  • A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G<sub>0</sub>/G<sub>1</sub> switch gene 2., Kamikubo K, Kato H, Kioka H, Yamazaki S, Tsukamoto O, Nishida Y, Asano Y, Imamura H, Kawahara H, Shintani Y, Takashima S, The Journal of biological chemistry,294(40) 14562-14573, 2019.10, Papers

  • Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation., Yamada N, Asano Y, Fujita M, Yamazaki S, Inanobe A, Matsuura N, Kobayashi H, Ohno S, Ebana Y, Tsukamoto O, Ishino S, Takuwa A, Kioka H, Yamashita T, Hashimoto N, Zankov DP, Shimizu A, Asakura M, Asanuma H, Kato H, Nishida Y, Miyashita Y, Shinomiya H, Naiki N, Hayashi K, Makiyama T, Ogita H, Miura K, Ueshima H, Komuro I, Yamagishi M, Horie M, Kawakami K, Furukawa T, Koizumi A, Kurachi Y, Sakata Y, Minamino T, Kitakaze M, Takashima S, Circulation,139(18) 2157-2169, 2019.04, Papers

  • Higd1a is a positive regulator of cytochrome c oxidase., Hayashi T, Asano Y, Shintani Y, Aoyama H, Kioka H, Tsukamoto O, Hikita M, Shinzawa-Itoh K, Takafuji K, Higo S, Kato H, Yamazaki S, Matsuoka K, Nakano A, Asanuma H, Asakura M, Minamino T, Goto Y, Ogura T, Kitakaze M, Komuro I, Sakata Y, Tsukihara T, Yoshikawa S, Takashima S, Proceedings of the National Academy of Sciences of the United States of America,2015 Feb 3;112(5):1553-8, 2015.02, http://www.pnas.org/cgi/doi/10.1073/pnas.1419767112, Papers

  • Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5., Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, Higo S, Yamazaki S, Shintani Y, Matsuoka K, Liao Y, Asanuma H, Asakura M, Takafuji K, Minamino T, Asano Y, Kitakaze M, Takashima S, Nature communications,6 6137, 2015.01, Other

  • Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart., Matsuoka K, Asano Y, Higo S, Tsukamoto O, Yan Y, Yamazaki S, Matsuzaki T, Kioka H, Kato H, Uno Y, Asakura M, Asanuma H, Minamino T, Aburatani H, Kitakaze M, Komuro I, Takashima S., FASEB J.,28(4):1870-9., 2014.04, Papers

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Patents / Utility models / Designs 【 display / non-display

  • Japan, noninvasive quatification methods of sequential monitoring the severity of heart faiure using transgenic mouse, Seiji Takashima, Yoshihiro Asano, Ken Matsuoka, Osamu Tsukamoto, Masafumi Kitakaze, 2013-228824 (2013-11-1)(Application), 2013.11

  • United States, Antagonists of neuropilin receptor function and use thereof, Seiji Takashima, US 7,335,357(Registration), 2006.07, 2008.02

  • United States, Neuropilins and use thereof in methods for diagnosis and prognosis of cancer, Seiji Takashima, US 6,635,421(Registration), 2000.05, 2003.10

  • United States, Method for diagnosing arrhythmogenic right ventricular dysplasia, Application No. 10/860,601(Application), 2004.06

 

Lecture / Exhibition 【 display / non-display

  • The 90th Annual Meeting of the Japanese Pharmacological Society, Allosteric Activation of Cytochrome C Oxidase by Small Ligands, 2017.03