School personnel information


NODA Takeshi


Autophagy, TORC1, Nutrition

Mail Address

Mail Address

Laboratory Phone number


Laboratory Fax number





Organization 【 display / non-display

  • 2006.02.01 - 2007.03.31, Research Institute for Microbial Diseases, Associate Professor

  • 2007.04.01 - 2010.03.31, Research Institute for Microbial Diseases, Associate Professor

  • 2010.04.01 - 2012.04.30, Department of Frontier Biosciences, Graduate School of Frontier Biosciences, Associate Professor

  • 2012.05.01 - , Center for Frontier Oral Science, Graduate School of Dentistry, Professor

  • 2010.04.01 - 2012.04.30, Division of Medicine, Graduate School of Medicine, Associate professor

  • 2012.06.01 - , Graduate School of Frontier Biosciences, Professor

Education 【 display / non-display

The University of Tokyo Faculty of Liberal Arts  Graduated 1991.03
The University of Tokyo Graduate School, Division of Science  Completed 1993.03
The University of Tokyo Graduate School, Division of General Culture  Completed Ph.D. 1996.03

Employment Record 【 display / non-display

National Institute for Basic Biology Assistant Professor 1996.04 - 2006.01
University of California San Diego, VIsiting Scientist 2003.05 - 2005.11

Research topics 【 display / non-display

  • Cell biology
    Cell biology-related, Oral biological science-related, Chemistry and chemical methodology of biomolecules-related


Academic Papers 【 display / non-display

  • Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan., Ikari S, Lu SL, Hao F, Imai K, Araki Y, Yamamoto YH, Tsai CY, Nishiyama Y, Shitan N, Yoshimori T, Otomo T, Noda T, PloS one,15(3) e0230156, 2020.04, Papers

  • Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells., Hsieh CL, Hsieh SY, Huang HM, Lu SL, Omori H, Zheng PX, Ho YN, Cheng YL, Lin YS, Chiang-Ni C, Tsai PJ, Wang SY, Liu CC, Noda T, Wu JJ, Frontiers in microbiology,11 117, 2020.02, Papers

  • Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy., Cheng YL, Kuo CF, Lu SL, Hiroko O, Wu YN, Hsieh CL, Noda T, Wu SR, Anderson R, Lin CF, Chen CL, Wu JJ, Lin YS, mBio,10(5), 2019.10, Papers

  • TORC1 as a hubTORC1 as a hub connecting nutrient availability with cell growth, Yasuhiro Araki, Takeshi NODA, Manufacturing & Technology,71(3) 77-80, 2019.07,, Review Papers(In Japanese)

  • Osteoblastic lysosome plays a central role in mineralization., Iwayama T, Okada T, Ueda T, Tomita K, Matsumoto S, Takedachi M, Wakisaka S, Noda T, Ogura T, Okano T, Fratzl P, Ogura T, Murakami S, <b>Science advances</b>,Vol. 5, no. 7, eaax0672, 2019.07, Other

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Books 【 display / non-display

  • Special, Monitoring autophagy in mammalian cultured cells through the dynamics of LC3. Methods Enzymol., Kimura S, Fujita N, Noda T, Yoshimori T., Academic Press,Inc., 2009.02

  • Special, Macroautophagy in Yeast in "AUTOPHAGY", Noda T. and Ohsumi Y, LANDES Bioscience, 2003.01


Lecture / Exhibition 【 display / non-display

  • the 14th International Congress on Yeasts, Study of termination mechanism of autophagy under prolonged starvation, 2016.09

  • The 4th Sino-Japan Symposium on Autophagy, Autophagy Regulation by Gtr-Gia-Tag Network, 2016.04

  • The 7th International Symposium on Autophagy, Genome-wide survey of the factors affecting autophagic activity, 2015.03

  • 2014 Northeastern Asian Symposium on Autophagy, Molecular mechanism involved in autophagy termination, 2014.12

  • Cell Signaling & Membrane Traffic Symposium, Regulation of autophagy by membrane traffic and TORC1, 2014.04

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Conference management 【 display / non-display

  • International Conference, the 6th international symposium on autophagy, Secretary general, 2012.10