School personnel information


NAKANO Kazuhiko

Date of Birth



Pediatric Dentistry, Dental caries, Infective endocarditis, Streptococcus mutans, Oral streptococci, Periodontal disease, Periodontal bacteria, Cardiovscular/Digestive diseases, Veterinary Dentistry

Mail Address

Mail Address

Laboratory Phone number


Laboratory Fax number





Organization 【 display / non-display

  • 2004.01.01 - 2007.03.31, Osaka University Dental Hospital, Research Assistant

  • 2007.04.01 - 2007.05.31, Osaka University Dental Hospital, Assistant Professor

  • 2007.06.01 - 2011.09.30, Osaka University Dental Hospital, Associate Professor

  • 2011.10.01 - 2012.03.31, Course for Molecular Oral Biology and Dentistry, Graduate School of Dentistry, Associate Professor

  • 2012.04.01 - 2014.07.31, Course for Oral Sciences, Graduate School of Dentistry, Associate Professor

  • 2014.08.01 - , Course for Oral Sciences, Graduate School of Dentistry, Professor

Education 【 display / non-display

Osaka University Faculty of Dentistry  Graduated DDS 1996.03
Osaka University   Completed PhD 2002.11

Employment Record 【 display / non-display

Research Student, Osaka University Faculty of Dentistry 1996.04 - 1996.05
Resident, Osaka University Dental Hospital 1996.06 - 1997.03
Clinical Instructor, Osaka University Dental Hospital 1997.04 - 2003.12
Research Associate, Osaka University Dental Hospital 2003.12 - 2007.03
Assistant Professor, Osaka University Dental Hospital 2007.04 - 2007.05
Associate Professor, Osaka University Dental Hospital 2007.05 - 2011.09
Associate Professor, Osaka University Graduate School of Dentistry 2011.10 - 2014.07
Professor 2014.08 -

Research topics 【 display / non-display

  • Transmission of periodontal bacteria between pets and their owners
    Conservative dentistry-related, Veterinary medical science-related

  • Association of oral bacteria with digestive diseases
    Bacteriology-related, Gastroenterology-related

  • Association of oral bacteria with cerebrovascular diseases
    Bacteriology-related, Neurosurgery-related

  • Investigation of properties of S. mutans isolated from patients with infective endocarditis
    Bacteriology-related, Cardiovascular surgery-related, Cardiology-related, Connective tissue disease and allergy-related

  • Designation of a novel serotype S. mutans and investigation of clinical significance

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Academic Society Membership 【 display / non-display

  • The Osaka University Dental Society

  • Japanese Association of Dental Reseach

  • International Association for Dental Research

  • The Japanese Society of Pediatric Dentistry


Academic Papers 【 display / non-display

  • Inhibition of Porphyromonas gingivalis and periodontal disease in dogs by a combination of clindamycin and interferon alpha., Nomura R, Inaba H, Yasuda H, Shirai M, Kato Y, Murakami M, Iwashita N, Shirahata S, Yoshida S, Matayashi S, Yasuda J, Arai N, Asai F, Matsumoto-Nakano M, Nakano K., Scientific Reports,10(1): 3113, 2020.02, Papers

  • Possible link between dental diseases and atherosclerosis in patients on hemodialysis. , Misaki T, Fukunaga A, Shimizu Y, Ishikawa A, Nakano K., PLoS ONE,14(12): e0225038, 2019.12, Papers

  • Presence of specific strains of Streptococcus mutans, a pathogen of dental caries, in the tonsils is associated with IgA nephropathy. , Ito S, Misaki T, Naka S, Wato K, Nagasawa Y, Nomura R, Otsugu M, Matsumoto-Nakano M, Nakano K, Kumagai H, Oshima N., Scientific Reports,9(1): 20130, 2019.12, Papers

  • Relationship between Streptococcus mutans expressing Cnm in the oral cavity and non-alcoholic steatohepatitis: A pilot study, 103. Tonomura S, Naka S, Tabata K, Hara T, Mori K, Tanaka S, Sumida Y, Kanemasa K, Nomura R, Matsumoto-Nakano M, Ihara M, Takahashi N, Nakano K. , BMJ Open Gastroenterology,6(1): e000329, 2019.10, Papers

  • Japanese nationwide survey of hypophosphatasia reveals prominent differences in genetic and dental findings between odonto and non-odonto types., Okawa R, Kokomoto K, Kitaoka T, Kubota T, Watanabe A, Taketani T, Michigami T, Ozono K, Nakano K., PLoS ONE,14(10): e0222931, 2019.10, Papers

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Awards 【 display / non-display

  • Best Original Article Award (Oral Diseases 2011), Nakano K, Wada K, Nomura R, Nemoto H, Inaba H, Kojima A, Naka S, Hokamura K, Mukai T, Nakajima A, Umemura K, Kamisaki Y, Yoshioka H, Taniguchi K, Amano A, Ooshima T., Oral Diseases, 2011.12

  • 2007 Lion Award, Kazuhiko Nakano, The Japanese Society of Pediatric Dentistry, 2007.07

  • 2003 JSPD Award for Young Investigator, Kazuhiko Nakano, The Japanese Society of Pediatric Dentistry, 2003.05


Lecture / Exhibition 【 display / non-display

  • Joint scientific syposium -Current and future challenges in dentistry, Novel guideline for prevention of infective endocarditis in Japan, 2019.03

  • Korean Society of Inherited Metabolic Diseases Seminar, Why is medical-dental collaboration important for early diagnosis and treatment of hypophosphatasia?, 2018.06

  • Samsung Medical Center Seminar, Oral manifestations in hypophosphatasia. What can pediatric dentists do?, 2018.06