School personnel information

写真b

TAKEHARA Tetsuo


Keyword

Cell Death, Innate Immunty, Viral Hepatitis, Hepatocellular Carcinoma

URL

http://www.med.osaka-u.ac.jp/pub/gh/index.html

Organization 【 display / non-display

  • 2001.04.01 - 2005.07.31, Division of Pathophysiology and Therapeutics, Graduate School of Medicine, Associate Professor

  • 2005.08.01 - 2007.03.31, Division of Internal Medicine, Graduate School of Medicine, Associate Professor

  • 2007.04.01 - 2011.03.31, Division of Internal Medicine, Graduate School of Medicine, Associate Professor

  • 2011.04.01 - , Division of Medicine, Graduate School of Medicine, Professor

Education 【 display / non-display

Osaka University Faculty of Medicine  Graduated 1984.03
Osaka University   Completed M.D. Ph.D. 1993.12

Employment Record 【 display / non-display

Osaka University Graduate School of Medicine, Department of Gastroenterology and Hepatology 2005.08 -
Osaka University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Associate Professor 2007.04 -
Professor and Chairman, Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine 2011.04 -

Academic Society Membership 【 display / non-display

  • Director, The Japan Society of Hepatology

  • Councilor, The Japanese Society of Gastroenterology

  • Councilor, The Japanese Society of Internal Medicine

 

Academic Papers 【 display / non-display

  • Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice., Kodama T, Takehara T, Hikita H, Shimizu S, Shigekawa M, Tsunematsu H, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Kubota S, Takigawa M, Tomimaru Y, Tomokuni A, Nagano H, Doki Y, Mori M, Hayashi N., The Journal of Clinical Investigation,121 (8): 3343-3356, 2011., 2011.08, Papers

  • The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib., Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N., Hepatology,52 (4): 1310-1321, 2010.10, Papers

  • Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice., Kodama T, Takehara T, Hikita H, Shimizu S, Wei Li, Miyagi T, Hosui A, Tatsumi T, Ishida H, Tadokoro S, Ido A, Tsubouchi H, Hayashi N., Gastroenterology,138: 2487-2498, 2010.06, Papers

  • Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver., Hikita H, Takehara T, Shimizu S, Kodama T, Li W, Miyagi T, Hosui A, Ishida H, Ohkawa K, Kanto T, Hiramatsu N, Yin XM, Hennighausen L, Tatsumi T, Hayashi N., Hepatology,50: 1217-1226, 2009.10, Papers

  • Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice., Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N., Hepatology,54 (1): 240-251, 2011.07, Papers

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Books 【 display / non-display

  • Other, Vitamin D add-on therapy to pegylated interferon and ribavirin in chronic hepatitis C, Takayuki Yakushijin, Tetsuo Takehara, 2011.02

  • Other, Hepatic hilar cyst and liver cirrhosis, Takayuki Yakushijin, Tetsuo Takehara, 2010.10

  • Special, Dendritic cells and hepatitis C virus. Prevention of progression in chronic liver disease, Norio Hayshi, Tatsuya Kanto, Tetsuo Takehara, Kluwer Academic Publishers, 2004.08

  • Special, Bcl-xL as a critical apoptosis antagonist in hepatocyte and hepatocellular carcinoma., Tetsuo Takehara, Norio Hayashi, Frontiers in Hepatology: Stem Cell and Liver Regeneration. Springer-Verlag Tokyo, 2004.01

  • Special, Cancer vaccination by B7-1-transfected hepatocellular carcinoma cells. Frontier in Hepatology: Progress in Hepatocellular Carcinoma Treatment., Tatsumi T, Takehara T, Sasaki Y, Hori M, Hayashi N., Springer-Verlag Tokyo, 2000.01

Awards 【 display / non-display

  • OTSUKA AWARD, Tetsuo Takehara, The Japan Society of Hepatology, 2009.10

 

Lecture / Exhibition 【 display / non-display

  • Choshu International Liver Symposium, Impact of Hepatocyte Apoptosis on Liver Carcinogenesis, 2013.02

  • The 10th JSH Single Topic Conference, Impact of liver injury on hepatocarcinogenesis in chronic hepatitis C, 2012.11