School personnel information

写真b

OBIKA Satoshi


Keyword

Bioorganic Chemistry

Mail Address

Mail Address

Gender

Male

Organization 【 display / non-display

  • 1998.04.01 - 2006.03.31, Applied Biopharamaceutical Sciences, Graduate School of Pharmaceutical Sciences, Research Assistant

  • 2006.04.01 - 2007.03.31, Applied Biopharamaceutical Sciences, Graduate School of Pharmaceutical Sciences, Associate Professor

  • 2007.04.01 - 2008.08.31, Applied Biopharamaceutical Sciences, Graduate School of Pharmaceutical Sciences, Associate Professor

  • 2008.09.01 - 2012.03.31, Applied Biopharamaceutical Sciences, Graduate School of Pharmaceutical Sciences, Professor

  • 2012.04.01 - 2013.03.31, Advanced Pharmaco-science, Graduate School of Pharmaceutical Sciences, Professor

  • 2013.04.01 - , Drug Innovation Center, Graduate School of Pharmaceutical Sciences, Professor

Education 【 display / non-display

Osaka University Faculty of Pharmaceutical Science  Graduated 1990.03
Osaka University Graduate School, Division of Pharmaceutical Sciences  Completed 1992.03

Employment Record 【 display / non-display

JST, PRESTO, Researcher 2004.10 - 2008.03
Associate Professor, Osaka University 2006.04 - 2008.08
Professor, Osaka University 2008.08 -

Academic Society Membership 【 display / non-display

  • The American Association for the Advancement of Science

  • International Society for Nucleosides, Nucleotides and Nucleic Acids

  • Oligonucleotide Therapeutics Society

 

Academic Papers 【 display / non-display

  • Design, Synthesis and Properties of 2’,4’-BNANC: A Bridged Nucleic Acid Analogue, S. M. A. Rahman, S. Seki, S. Obika, H. Yoshikawa, K. Miyashita and T. Imanishi, J. Am. Chem. Soc.,130, 4886-4896, 2008.03, Papers

  • Recognition of T・A Interruption by 2’,4’-BNAs Bearing Heteroaromatic Nucleobases Through Parallel Motif Triplex Formation, S. Obika, H. Inohara, Y. Hari and T. Imanishi, Bioorg. Med. Chem.,16, 2945-2954, 2008.02, Papers

  • Biologically Stable 2-5A Analogues Containing 3’-O,4’-C-Bridged Adenosine as Potent RNase L Agonists, K. Morita, M. Kaneko, S. Obika, T. Imanishi, Y. Kitade and M. Koizumi, ChemMedChem,2, 1703-1707, 2007.11, Papers

  • N-Methyl Substituted 2’,4’-BNANC: A Highly Nuclease-resistance Nucleic Acid Analogue with High-affinity RNA Selective Hybridization, K. Miyashita, S. M. A. Rahman, S. Seki, S. Obika and T. Imanishi, Chem. Commun.,3765-3767, 2007.11, Papers

  • Double-stranded DNA-templated Oligonucleotide Digestion Triggered by Triplex Formation, S. Obika, M. Tomizu, Y. Negoro, A. Orita, O. Nakagawa and T. Imanishi, ChemBioChem,8, 1924-1928, 2007.09, Papers

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Books 【 display / non-display

  • Special, Sugar-Modified Nucleic Acid Analogues as Potential Materials for Genomic Technologies, T. Imanishi and S. Obika, Frontiers in Organic Chemistry, 2005.07

  • Special, Effect of Modifications on the Intracellular Activity of a DNA Enzyme, M. Warashina, B. Nawrot, S. Obika, L. A. Woniak, T. Kuwabara, T. Imanishi, W. J. Stec and K. Taira, Synthetic Nucleic Acids as Inhibitors of Gene Expression, 2005.05

  • Special, 2'-O,4'-C-Methyleneoxymethylene Bridged Nucleic Acid (2',4'-BNACOC), Y. Hari, T. Kodama, T. Imanishi, S. Obika, Humana Press, ISBN, 978-1617791871, 2011.07

 

Lecture / Exhibition 【 display / non-display

  • 12th Annual Meeting of the Oligonucleotide Therapeutics Society, 2016.09