School personnel information


KON Takahide


Biophysics, Structural biology, Molecular motor, Intracellular trafficking, Ciliogenesis


Organization 【 display / non-display

  • 2010.10.01 - 2013.03.31, Institute for Protein Research, Associate Professor

  • 2015.04.01 - , Department of Biological Sciences, Graduate School of Science, Professor

Education 【 display / non-display

The University of Tokyo Graduate School, Division of General Culture  Completed Ph.D. 2000.03

Employment Record 【 display / non-display

Research Associate, Graduate School of Arts and Sciences, University of Tokyo 2000.04 - 2007.03
Assistant Professor, Graduate School of Arts and Sciences, University of Tokyo 2007.04 - 2010.09

Research topics 【 display / non-display

  • Structural basis for intracellular trafficking
    Structural biochemistry-related, Biophysics-related, Molecular biology-related

  • Studies on force generating mechanism of molecular motors
    Biophysics-related, Structural biochemistry-related, Functional biochemistry-related

  • Molecular mechanism of cell motility
    Structural biochemistry-related, Cell biology-related, Molecular biology-related

Academic Society Membership 【 display / non-display

  • The Biophysical Society of Japan

  • Biophysical Society

  • The American Society for Cell Biology

  • The Crystallographic Society of Japan

  • Protein Science Society of Japan


Academic Papers 【 display / non-display

  • Structural and Functional Analysis of the Dynein Motor Domain, Shima, Kon, T., Handbook of Dynein 2nd edition, 37-66, 2019.05, Review Papers

  • Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and propermorphology of inner dynein arms, Yamamoto, R., Obbineni, J.M., Alford, L.M., Ide, T., Owa, M., Hwang, J., Kon, T., Inaba, K., James, N., King, S.M., Ishikawa, T., Sale, W.S., Dutcher, S.K., PLoS Genet.,13(10) e1007063, 2017.09, Papers

  • Elastic properties of dynein motor domain obtained from all-atom molecular dynamics simulations., Kamiya, N., Mashimo, T., Takano, Y., Kon, T., Kurisu, G., Nakamura, H., Protein Engineering, Design, and Selection,2016, 1-9, 2016.06, Papers

  • Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules, Hiroshi Imai, Tomohiro Shima, Kazuo Sutoh, Matthew L. Walker, Peter J. Knight, Takahide Kon & Stan A. Burgess, Nature Communications,Nature Communications 6, Article number: 8179 (2015), 2015.09,, Papers

  • A flipped ion pair at the dynein-microtubule interface is critical for dynein motility and ATPase activation., Uchimura S, Fujii T, Takazaki H, Ayukawa R, Nishikawa Y, Minoura I, Hachikubo Y, Kurisu G, Sutoh K, Kon T, Namba K, Muto E, The Journal of cell biology,208(2) 211-222, 2015.01,, Papers

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