Details of a Researcher

写真b

OKADA Yoshiaki

Keyword	Endothelial cell, Robo4, Gene regulation, Epigenetics, vascular permeability
URL	http://www.phs.osaka-u.ac.jp/homepage/b018/

2006.07.01 - 2007.03.31, Center for Advanced Eduction and Research in Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Research Assistant
2007.04.01 - 2011.03.31, Center for Advanced Eduction and Research in Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Assistant Professor
2011.04.01 - 2012.03.31, Environmental Pharamaceutical Sciences, Graduate School of Pharmaceutical Sciences, Assistant Professor
2012.04.01 - 2012.05.15, Graduate School of Pharmaceutical Sciences, Assistant Professor
2012.05.16 - , Medical Pharmacy, Graduate School of Pharmaceutical Sciences, Associate Professor

Osaka University Faculty of Pharmaceutical Science Graduated		1998.03
Osaka University Graduate School, Division of Pharmaceutical Sciences Completed		2000.03
Osaka University Graduate School, Division of Pharmaceutical Sciences Completed	Ph.D.	2003.03

Beth Israel Deaconess Medical Center/Harvard Medical School

2003.09 - 2006.06

Function of endothelial cell-specific receptor, Robo4 in inflammation
Pharmaceutical hygiene and biochemistry-related
New strategy for anti-inflammatory and anti-cancer therapy targeting Robo4
Pharmaceutical hygiene and biochemistry-related
Endothelial cell type-specific gene expression regulated by transcription factors and epigenetic controls.
Pharmaceutical hygiene and biochemistry-related
Pharmaceutical hygiene and biochemistry-related

PRC2 components maintain DNA hypermethylation of the upstream promoter and regulate Robo4 expression in endothelial cells, Izawa K, Shirakura K, Kakiuchi K, Funahashi N, Maekawa N, Hino N, Tanaka T, Doi T, Okada Y., Biol Pharm Bull.，in press, 2020.01, Papers
The CalcR-PKA-Yap1 axis is critical for maintaining quiescence in muscle stem cells, Zhang L, Noguchi Y, Nakayama H, Kaji T, Tsujikawa K, Ikemoto-Uezumi M, Uezumi A, Okada Y, Doi T, Watanabe S, Braun T, Fujio T, Fukada SI, Cell Reports, 2019.10, Papers
Lipid nanoparticles of Type-A CpG D35 suppress tumor growth by changing tumor immune-microenvironment and activate CD8 T cells in mice, Munakata L, Tanimoto Y, Osa A, Meng J, Haseda Y, Naito Y, Machiyama H, Kumanogoh A, Omata D, Maruyama K, Yoshioka Y, Okada Y, Koyama S, Suzuki R, Aoshi T., Journal of Controlled Release, 2019.09, Papers
Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites, Noguchi Y, Nakamura M, Hino N, Nogami J, Tsuji S, Sato T, Zhang L, Tsujikawa K, Tanaka T, Izawa K, Okada Y, Doi T, Kokubo H, Harada A, Uezumi A, Gessler M, Ohkawa Y, Fukada SI, Development，in press, 2019.02, Papers
Lipin-1 is a novel substrate of protein phosphatase PGAM5., 1. Okuno H, Okuzono H, Hayase A, Kumagai F, Tanii S, Hino N, Okada Y, Tachibana K, Doi T., 2019.01, Papers

The Pharmaceutical Society of Japan Award for Young Scientists, Yoshiaki Okada, The Pharmaceutical Society of Japan, 2013.03