School personnel information

写真b

OKADA Yoshiaki


Keyword

Endothelial cell, Robo4, Gene regulation, Epigenetics, vascular permeability

URL

http://www.phs.osaka-u.ac.jp/homepage/b018/

Organization 【 display / non-display

  • 2006.07.01 - 2007.03.31, Center for Advanced Eduction and Research in Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Research Assistant

  • 2007.04.01 - 2011.03.31, Center for Advanced Eduction and Research in Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Assistant Professor

  • 2011.04.01 - 2012.03.31, Environmental Pharamaceutical Sciences, Graduate School of Pharmaceutical Sciences, Assistant Professor

  • 2012.04.01 - 2012.05.15, Graduate School of Pharmaceutical Sciences, Assistant Professor

  • 2012.05.16 - , Medical Pharmacy, Graduate School of Pharmaceutical Sciences, Associate Professor

Education 【 display / non-display

Osaka University Faculty of Pharmaceutical Science  Graduated 1998.03
Osaka University Graduate School, Division of Pharmaceutical Sciences  Completed 2000.03
Osaka University Graduate School, Division of Pharmaceutical Sciences  Completed Ph.D. 2003.03

Employment Record 【 display / non-display

Beth Israel Deaconess Medical Center/Harvard Medical School 2003.09 - 2006.06

Research topics 【 display / non-display

  • Function of endothelial cell-specific receptor, Robo4 in inflammation
    Pharmaceutical hygiene and biochemistry-related

  • New strategy for anti-inflammatory and anti-cancer therapy targeting Robo4
    Pharmaceutical hygiene and biochemistry-related

  • Endothelial cell type-specific gene expression regulated by transcription factors and epigenetic controls.
    Pharmaceutical hygiene and biochemistry-related

  • Pharmaceutical hygiene and biochemistry-related

Academic Society Membership 【 display / non-display

  • The Japanese Vascular Biology and Medicine Organization

 

Academic Papers 【 display / non-display

  • PRC2 components maintain DNA hypermethylation of the upstream promoter and regulate Robo4 expression in endothelial cells, Izawa K, Shirakura K, Kakiuchi K, Funahashi N, Maekawa N, Hino N, Tanaka T, Doi T, Okada Y., Biol Pharm Bull.,in press, 2020.01, Papers

  • The CalcR-PKA-Yap1 axis is critical for maintaining quiescence in muscle stem cells, Zhang L, Noguchi Y, Nakayama H, Kaji T, Tsujikawa K, Ikemoto-Uezumi M, Uezumi A, Okada Y, Doi T, Watanabe S, Braun T, Fujio T, Fukada SI, Cell Reports, 2019.10, Papers

  • Lipid nanoparticles of Type-A CpG D35 suppress tumor growth by changing tumor immune-microenvironment and activate CD8 T cells in mice, Munakata L, Tanimoto Y, Osa A, Meng J, Haseda Y, Naito Y, Machiyama H, Kumanogoh A, Omata D, Maruyama K, Yoshioka Y, Okada Y, Koyama S, Suzuki R, Aoshi T., Journal of Controlled Release, 2019.09, Papers

  • Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites, Noguchi Y, Nakamura M, Hino N, Nogami J, Tsuji S, Sato T, Zhang L, Tsujikawa K, Tanaka T, Izawa K, Okada Y, Doi T, Kokubo H, Harada A, Uezumi A, Gessler M, Ohkawa Y, Fukada SI, Development,in press, 2019.02, Papers

  • Lipin-1 is a novel substrate of protein phosphatase PGAM5., 1. Okuno H, Okuzono H, Hayase A, Kumagai F, Tanii S, Hino N, Okada Y, Tachibana K, Doi T., 2019.01, Papers

display all >>

Awards 【 display / non-display

  • The Pharmaceutical Society of Japan Award for Young Scientists, Yoshiaki Okada, The Pharmaceutical Society of Japan, 2013.03