School personnel information


KODAMA Takahiro


HCC, PDAC, gastroenterology, Hepatology, cancer genome

Mail Address

Mail Address


Organization 【 display / non-display

  • 2016.06.01 - , Division of Medicine, Graduate School of Medicine, Assistant Professor

Education 【 display / non-display

Osaka University Faculty of Medicine  Graduated 2002.03
Osaka University Graduate School, Division of Medical Sciences  Completed Doctor (Medicine) 2011.03

Employment Record 【 display / non-display

Houston Methodist Research Institute Postdoctoral associate 2012.07 - 2016.05

Research topics 【 display / non-display

  • Discovery of new therapeutic targets and biomarkers regarding hepatobiliary and pancreatic neoplasms, through the elucidation of molecular mechanisms of their development, progression, metastasis and drug resistance by mouse in vivo forward genetic screen and analysis of human clinical specimens,
    Gastroenterology-related, Tumor biology-related, Medical biochemistry-related

Academic Society Membership 【 display / non-display

  • AACR



Academic Papers 【 display / non-display

  • DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway., Saito Y, Hikita H, Nozaki Y, Kai Y, Makino Y, Nakabori T, Tanaka S, Yamada R, Shigekawa M, Kodama T, Sakamori R, Tatsumi T, Takehara T, Cell Death and Differentiation,26(3):470-486, 2019.03, Papers

  • Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis., Kodama T, Yi J, Newberg JY, Tien JC, Wu H, Finegold MJ, Kodama M, Wei Z, Tamura T, Takehara T, Johnson RL, Jenkins NA, Copeland NG, Proceeding of the National Academy of Sciences of the United States of America,115(44):E10417-E10426, 2018.10, Papers

  • Autophagy impairment in pancreatic acinar cells causes zymogen granule accumulation and pancreatitis., Iwahashi K, Hikita H, Makino Y, Shigekawa M, Ikezawa K, Yoshioka T, Kodama T, Sakamori R, Tatsumi T, Takehara T, Biochemical and Biophysical Research Communications,503(4):2576-2582, 2018.09, Papers

  • CEACAM1 Is Associated With the Suppression of Natural Killer Cell Function in Patients With Chronic Hepatitis C., Suda T, Tatsumi T, Nishio A, Kegasawa T, Yoshioka T, Yamada R, Furuta K, Kodama T, Shigekawa M, Hikita H, Sakamori R, Fukuhara T, Matsuura Y, Takehara T, Hepatology Communications,2(10):1247-1258, 2018.09, Papers

  • Immunological responses against hepatitis B virus in human peripheral blood mononuclear cell-engrafted mice., Aono S, Tatsumi T, Yoshioka T, Tawara S, Nishio A, Onishi Y, Fukutomi K, Nakabori T, Kodama T, Shigekawa M, Hikita H, Sakamori R, Takahashi T, Suemizu H, Takehara T, Biochemical and Biophysical Research Communications,503(3):1457-1464, 2018.09, Papers

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