School personnel information

写真b

AKAI Shuji


Keyword

synthetic organic chemistry, medicinal chemistry, catalyst, asymmetric synthesis, total synthesis

Mail Address

 Mail Address

URL

http://handai-seizo.jp/

Gender

Male
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Organization 【 display / non-display 】

  • 2012.12.16 - 2013.03.15, The Institute of Scientific and Industrial Research, Specially Appointed Researcher

  • 2013.03.16 - , Medical Pharmacy, Graduate School of Pharmaceutical Sciences, Professor

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Education 【 display / non-display 】

Osaka University Graduate School, Division of Pharmaceutical Sciences  Completed 1987.03
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Employment Record 【 display / non-display 】

National Institute of Biomedical Innovation, Technical Advisor 2014.04 -
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Research topics 【 display / non-display 】

  • 1. Synthesis of bioactive natural products
    2. Development of new methods for asymmetric synthesis using enzyme catalysis
    3. Regiocontrol of aryne reactions and its synthetic applications
    4. Creation of new bio functional molecules for drug discovery and/or medical treatment
    Pharmaceutical chemistry and drug development sciences-related, Pharmaceutical chemistry and drug development sciences-related, Synthetic organic chemistry-related, Structural organic chemistry and physical organic chemistry-related, Biofunction and bioprocess engineering-related

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Academic Papers 【 display / non-display 】

  • Lipase-Catalyzed Dynamic Kinetic Resolution of C1- and C2-Symmetric Racemic Axially Chiral 2,2’-Dihydroxy-1,1’-biaryls, Gamal A. I. Moustafa, Yasuhiro Oki, Shuji Akai, Angew. Chem. Int. Ed.，57.10278-10282, 2018.04, Papers

  • One-Pot Generation of Functionalized Benzynes from Readily Available 2-Hydroxyphenylboronic Acids, Takashi Ikawa, JingKai Sun, Akira Takagi, Shuji Akai, The Journal of Organic Chemistry, 2020.02, Papers

  • One-Pot Generation of Benzynes from Phenols: Formation of Primary Anilines by the Deoxyamination of Phenols, Takashi Ikawa, Shigeaki Masuda, and Shuji Akai, Chemistry A European Journal, 2019.12, Papers

  • Correlation of indoleamine-2,3-dioxigenase 1 inhibitory activity of 4,6-disubstituted indazole derivatives and their heme binding affinity., Tsujino H, Uno T, Yamashita T, Katsuda M, Takada K, Saiki T, Maeda S, Takagi A, Masuda S, Kawano Y, Meguro K, Akai S, Bioorganic & medicinal chemistry letters，29(19) 126607, 2019.10, Other

  • Ammonium Salt-Accelerated Hydrazinolysis of Unactivated Amides: Mechanistic Investigation and Application to a Microwave Flow Process, Megumi Noshita, Yuhei Shimizu, Hiroyuki Morimoto, Shuji Akai, Yoshitaka Hamashima, Noriyuki Ohneda, Hiromichi Odajima, and Takashi Ohshima, Org. Process Res. Dev.，23, 588–594, 2019.03, Papers

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Patents / Utility models / Designs 【 display / non-display 】

  • Japan, Boronia-like fragrance composition, Komaki, Ryoichi; Akai, Shuji; Igawa, Takashi; Egi, Masahiro, 6099141(Registration), 2013.05, 2017.03

  • Japan, Blue lotus-like fragrance compositions containing b-ionone, b-ionol, and b-phenylethyl alcohol and food and cosmetics, Komaki, Ryoichi; Akai, Shuji; Igawa, Takashi; Egi, Masahiro, 特開2014-227383(Publication), 2013.05

  • Japan, Melanin generation inhibitor and skin-whitening cosmetic containing beta-ionol , Akai, Shuji; Igawa, Takashi; Egi, Masahiro; Komaki, Ryoichi, 特開2014-114231(Publication), 2012.12

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Conference management 【 display / non-display 】

  • International Conference, The 27th International Society of Heterocyclic Chemistry Congress, 2019.09

  • International Conference, The 10th Seoul-Kyoto-Osaka Joint Symposium, 2017.05

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